Jacob Chacko MD

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Jacob Chacko MD

Dr. Chacko has served as CEO of ORIC Pharmaceuticals since April 2018. During Dr. Chacko’s tenure, ORIC has raised over $600mm in private and public financing, including its IPO in April 2020, and has advanced four programs into clinical trials. Prior to ORIC, Dr. Chacko was most recently CFO of Ignyta, a Nasdaq-listed precision oncology company acquired by Roche for $1.9 billion in February 2018. At Ignyta, he had a broad operational role and helped raise over $500 million in capital. Prior to Ignyta, Dr. Chacko was an investor at TPG Capital, where he helped lead teams that completed acquisitions having an aggregate value of over $10 billion. Prior to that, he was a consultant serving healthcare clients at McKinsey & Company.

Dr. Chacko currently serves on the board of directors of 4D Molecular Therapeutics (Nasdaq: FDMT) and chairs the Western Regional Selection Committee for the Marshall Scholarship. He previously served on the board of directors of Turning Point Therapeutics (Nasdaq: TPTX), Bonti (acquired by Allergan), EnvisionRx (acquired by Rite Aid), RentPath, and the Packard Children’s Health Alliance at the Lucile Packard Children’s Hospital Stanford; and he was a board observer to Par Pharmaceutical (acquired by Endo), IMS Health and Quintiles Transnational.

Dr. Chacko concurrently received his MD with AOA honors from UCLA and his MBA with Distinction from Harvard Business School. He also received a MSc from Oxford University as a Marshall Scholar and undergraduate degrees from the University of Southern California, where he graduated as the University Valedictorian.